GSE70425
What We Learned
  • An estimated one-third of the world’s population is currently latently infected with Mycobacterium tuberculosis.
  • Latent M. tuberculosis infection (LTBI) progresses into active tuberculosis (TB) disease in ~5 to 10% of infected individuals.
  • Diagnostic and prognostic biomarkers to monitor disease progression are urgently needed to ensure better care for TB patients and to decrease the spread of TB.
What We Did
  • A classification model has been built using Trainset. The selected probes were:
    1. hsa-mir-3607-3p
    2. hsa-mir-15b*
    3. hsa-let-7b
    4. hsa-mir-519e
  • The model has been tested using Testset.